FK506 Binding Protein 2, 13kDa (FKBP2) (N-Term) Peptide
FKBP2
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN976871
Aperçu rapide pour FK506 Binding Protein 2, 13kDa (FKBP2) (N-Term) Peptide (ABIN976871)
Antigène
FKBP2
(FK506 Binding Protein 2, 13kDa (FKBP2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-FKBP2 antibody (Catalog #: ARP58465_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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FK506 Binding Protein 2, 13kDa (FKBP2) (AA 22-142) peptide
FKBP2 Reactivité: Humain Hôte: Escherichia coli (E. coli) SDS Dithiothreitol (DTT)
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))
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Sujet
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FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.
Alias Symbols: FKBP-13, PPIase
Protein Interaction Partner: ARFGEF1,BAT3,C1QC,EPB41,EPB41L2,UBQLN4,ARFGEF1,ARFGEF2,BAT3,CDKN2A,EPB41L2
Protein Size: 142 -
Poids moléculaire
- 16 kDa
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ID gène
- 2286
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NCBI Accession
- NM_004470, NP_004461
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UniProt
- P26885
Antigène
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